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CMap Candidate Details

Structure:
CMap ID: C00285
Pert ID: BRD-A28318179
Compound Name: aminomethyltransferase
Targets: NOS2
MoA: nitric oxide synthase inhibitor
SMILES: CC1CCN=C(N)S1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1686 BRD-A28318179 HA1E 10 uM 6 h 0.18 0.75 0.0 -0.24 -0.82 0.15
1818 BRD-A28318179 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
2328 BRD-A28318179 PC3 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.13 1.0
2722 BRD-A28318179 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41658 BRD-A28318179 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42005 BRD-A28318179 A549 10 uM 6 h -0.27 -1.12 0.38 -0.36 -1.2 1.2
42537 BRD-A28318179 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42844 BRD-A28318179 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43256 BRD-A28318179 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43393 BRD-A28318179 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43707 BRD-A28318179 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).