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CMap Candidate Details

Structure:
CMap ID: C02854
Pert ID: BRD-K45446451
Compound Name: JZL-184
Targets: MGLL
MoA: monoacylglucerol lipase inhibitor
SMILES: OC(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)(c1ccc2OCOc2c1)c1ccc2OCOc2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8943 BRD-K45446451 A375 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9205 BRD-K45446451 A549 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9429 BRD-K45446451 AGS 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9921 BRD-K45446451 HA1E 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10170 BRD-K45446451 HCC515 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10521 BRD-K45446451 HCT116 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10789 BRD-K45446451 HEPG2 12 uM 6 h 0.23 0.98 0.09 -0.27 -0.91 0.31
10976 BRD-K45446451 HT29 12 uM 24 h -0.2 -0.84 0.0 -0.22 -0.73 0.04
11177 BRD-K45446451 MCF??7.00 12 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.19
11493 BRD-K45446451 NCIH2073 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11771 BRD-K45446451 NCIH508 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12323 BRD-K45446451 NOMO1 12 uM 6 h 0.0 0.0 0.0 0.38 1.36 1.72
12493 BRD-K45446451 PC3 12 uM 24 h -0.28 -1.17 0.48 0.0 0.0 0.0
12797 BRD-K45446451 SW480 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13011 BRD-K45446451 THP1 12 uM 6 h 0.26 1.08 0.21 0.0 0.0 0.0
13278 BRD-K45446451 U937 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13477 BRD-K45446451 VCAP 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).