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CMap Candidate Details

Structure:
CMap ID: C02861
Pert ID: BRD-A67748489
Compound Name: K-858
Targets: KIF11
MoA: kinesin-like spindle protein inhibitor
SMILES: CC(=O)NC1=NN(C(C)=O)C(C)(S1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33581 BRD-A67748489 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34002 BRD-A67748489 ASC 10 uM 24 h 0.25 1.03 0.14 -0.26 -0.88 0.26
34279 BRD-A67748489 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34515 BRD-A67748489 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34785 BRD-A67748489 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35058 BRD-A67748489 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35275 BRD-A67748489 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
35695 BRD-A67748489 NPC 10 uM 24 h -0.21 -0.89 0.04 0.0 0.0 0.0
36159 BRD-A67748489 PHH 10 uM 24 h 0.18 0.76 0.0 -0.32 -1.08 0.8
36454 BRD-A67748489 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36741 BRD-A67748489 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96089 BRD-A67748489 A549 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
97070 BRD-A67748489 PC3 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).