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CMap Candidate Details

Structure:
CMap ID: C02875
Pert ID: BRD-A97739905
Compound Name: ketoprofen
Targets: CXCR1|PTGS1|PTGS2|SLC5A8
MoA: cyclooxygenase inhibitor
SMILES: CC(C(O)=O)c1cccc(c1)C(=O)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4533 BRD-A97739905 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4869 BRD-A97739905 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37572 BRD-A97739905 ASC 10 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
37864 BRD-A97739905 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38411 BRD-A97739905 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38677 BRD-A97739905 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90931 BRD-A97739905 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.22 0.77 0.05
128153 BRD-A97739905 A549 0.37 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
128245 BRD-A97739905 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128273 BRD-A97739905 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.39 1.37 2.08
128324 BRD-A97739905 MDAMB231 1.11 uM 24 h -0.21 -0.89 0.03 0.0 0.0 0.0
128365 BRD-A97739905 THP1 1.11 uM 24 h -0.3 -1.24 0.67 -0.26 -0.87 0.23
135763 BRD-A97739905 A375 0.74 uM 24 h 0.22 0.93 0.05 -0.23 -0.76 0.07
135829 BRD-A97739905 HA1E 0.08 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
135867 BRD-A97739905 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135919 BRD-A97739905 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135957 BRD-A97739905 HT29 0.01 uM 24 h 0.19 0.81 0.0 0.0 0.0 0.0
136009 BRD-A97739905 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
136070 BRD-A97739905 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.06
136155 BRD-A97739905 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).