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CMap Candidate Details

Structure:
CMap ID: C00290
Pert ID: BRD-K80267133
Compound Name: aminosalicylate
Targets: ALOX5|CHUK|PLA2G2E|PTGS1|PTGS2
MoA: cyclooxygenase inhibitor
SMILES: Nc1ccc(C(O)=O)c(O)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
52198 BRD-K80267133 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91350 BRD-K80267133 HUH7 20 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
125996 BRD-K80267133 HA1E 0.04 uM 24 h 0.16 0.69 0.0 0.0 0.0 0.0
126109 BRD-K80267133 JURKAT 10 uM 24 h -0.25 -1.04 0.21 -0.22 -0.73 0.04
126164 BRD-K80267133 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126230 BRD-K80267133 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126252 BRD-K80267133 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.19 0.66 0.01
126282 BRD-K80267133 THP1 3.33 uM 24 h 0.24 0.98 0.09 -0.28 -0.93 0.34
133995 BRD-K80267133 A375 2.22 uM 24 h 0.34 1.4 1.02 0.0 0.0 0.0
134028 BRD-K80267133 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134083 BRD-K80267133 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134136 BRD-K80267133 HELA 0.03 uM 24 h -0.21 -0.89 0.03 -0.3 -1.01 0.56
134172 BRD-K80267133 HT29 0.01 uM 24 h 0.2 0.84 0.0 0.38 1.35 1.72
134200 BRD-K80267133 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134303 BRD-K80267133 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).