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CMap Candidate Details

Structure:
CMap ID: C02923
Pert ID: BRD-A12237696
Compound Name: L-Citrulline
Targets: ASS1|DDAH1|DDAH2|GPRC6A|NOS1|NOS2|NOS3|OTC|PADI1|PADI2|PADI3|PADI4|PADI6
MoA: nitric oxide stimulant
SMILES: NC(CCCNC(N)=O)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122235 BRD-A12237696 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122278 BRD-A12237696 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122351 BRD-A12237696 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
122457 BRD-A12237696 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122506 BRD-A12237696 YAPC 1.11 uM 24 h 0.25 1.04 0.15 0.19 0.68 0.01
130579 BRD-A12237696 HA1E 0.25 uM 24 h 0.25 1.02 0.13 0.26 0.92 0.25
130610 BRD-A12237696 HEK293 0.08 uM 24 h -0.31 -1.3 0.81 0.0 0.0 0.0
130651 BRD-A12237696 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130691 BRD-A12237696 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.2
130754 BRD-A12237696 MCF??7.00 0.74 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
130776 BRD-A12237696 MDAMB231 0.01 uM 24 h -0.22 -0.94 0.08 0.0 0.0 0.0
130803 BRD-A12237696 PC3 0.01 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).