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CMap Candidate Details

Structure:
CMap ID: C02948
Pert ID: BRD-K89402695
Compound Name: L-655240
Targets: PTGES
MoA: thromboxane receptor antagonist
SMILES: Cc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(F)cc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2006 BRD-K89402695 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2527 BRD-K89402695 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39362 BRD-K89402695 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40107 BRD-K89402695 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40915 BRD-K89402695 NEU 10 uM 24 h 0.2 0.84 0.0 -0.31 -1.03 0.65
41238 BRD-K89402695 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41578 BRD-K89402695 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121751 BRD-K89402695 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121830 BRD-K89402695 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121858 BRD-K89402695 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129775 BRD-K89402695 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129859 BRD-K89402695 HEK293 0.25 uM 24 h -0.23 -0.97 0.11 0.0 0.0 0.0
129886 BRD-K89402695 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129906 BRD-K89402695 HT29 0.08 uM 24 h 0.33 1.39 1.02 -0.33 -1.13 0.97
129932 BRD-K89402695 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.91
129983 BRD-K89402695 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130070 BRD-K89402695 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
130141 BRD-K89402695 THP1 2.22 uM 24 h -0.21 -0.85 0.01 0.0 0.0 0.0
130176 BRD-K89402695 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).