CMap Candidate Details
Structure:
| CMap ID: | C02950 |
| Pert ID: | BRD-K74284736 |
| Compound Name: | L-689560 |
| Targets: | GRIN1|GRIN2A|GRIN2B|GRIN2C|GRIN2D |
| MoA: | glutamate receptor antagonist |
| SMILES: | OC(=O)[C@H]1C[C@H](NC(=O)Nc2ccccc2)c2c(Cl)cc(Cl)cc2N1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1621 | BRD-K74284736 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.16 | 1.1 |
| 2119 | BRD-K74284736 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2419 | BRD-K74284736 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2517 | BRD-K74284736 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42140 | BRD-K74284736 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.19 | -0.63 | 0.01 |
| 42466 | BRD-K74284736 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42776 | BRD-K74284736 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 43070 | BRD-K74284736 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 43232 | BRD-K74284736 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.39 | 1.37 | 2.06 |
| 43644 | BRD-K74284736 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 43943 | BRD-K74284736 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.85 | 0.14 |
| 44198 | BRD-K74284736 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.14 | 1.03 |
| 99456 | BRD-K74284736 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |