Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C02951
Pert ID: BRD-K28470988
Compound Name: L-690330
Targets: IMPA1
MoA: inositol monophosphatase inhibitor
SMILES: CC(Oc1ccc(O)cc1)(P(O)(O)=O)P(O)(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8928 BRD-K28470988 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9194 BRD-K28470988 A549 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.23 1.25
9400 BRD-K28470988 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9967 BRD-K28470988 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
10215 BRD-K28470988 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 1.01
10495 BRD-K28470988 HCT116 10 uM 6 h -0.18 -0.74 0.0 0.0 0.0 0.0
10768 BRD-K28470988 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11462 BRD-K28470988 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.25 1.35
12026 BRD-K28470988 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.58
12539 BRD-K28470988 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
13250 BRD-K28470988 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13466 BRD-K28470988 VCAP 10 uM 24 h 0.0 0.0 0.0 0.35 1.25 1.29
96053 BRD-K28470988 PHH 1.11 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
98804 BRD-K28470988 NPC 10 uM 6 h 0.19 0.81 0.0 -0.22 -0.73 0.04
99023 BRD-K28470988 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121974 BRD-K28470988 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121995 BRD-K28470988 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122027 BRD-K28470988 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122080 BRD-K28470988 HUVEC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122097 BRD-K28470988 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122126 BRD-K28470988 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130380 BRD-K28470988 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130468 BRD-K28470988 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.65
130511 BRD-K28470988 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.89
130542 BRD-K28470988 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.62
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).