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CMap Candidate Details

Structure:
CMap ID: C02952
Pert ID: BRD-K83322645
Compound Name: L-693403
Targets: DRD2|SIGMAR1
MoA: sigma receptor agonist; sigma receptor antagonist
SMILES: C(N1CCC2(CCc3ccccc23)CC1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2930 BRD-K83322645 HA1E 10 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
3271 BRD-K83322645 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3550 BRD-K83322645 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3876 BRD-K83322645 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39200 BRD-K83322645 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39352 BRD-K83322645 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39789 BRD-K83322645 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40081 BRD-K83322645 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40346 BRD-K83322645 HT29 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.24 1.3
40647 BRD-K83322645 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40888 BRD-K83322645 NEU 10 uM 24 h -0.21 -0.88 0.03 -0.23 -0.77 0.08
41209 BRD-K83322645 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41548 BRD-K83322645 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).