CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02955
Pert ID:	BRD-K08109516
Compound Name:	L-701324
Targets:	GRIN1\|GRIN2A\|GRIN2B\|GRIN2C\|GRIN2D
MoA:	glutamate receptor antagonist
SMILES:	Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5180	BRD-K08109516	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5428	BRD-K08109516	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5574	BRD-K08109516	HCC515	10 uM	24 h	0.18	0.76	0.0	-0.25	-0.84	0.17
5880	BRD-K08109516	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6003	BRD-K08109516	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6082	BRD-K08109516	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6260	BRD-K08109516	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6309	BRD-K08109516	VCAP	10 uM	24 h	0.25	1.03	0.13	0.0	0.0	0.0
42050	BRD-K08109516	A549	10 uM	6 h	-0.23	-0.98	0.11	0.32	1.13	0.85
42280	BRD-K08109516	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
43474	BRD-K08109516	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
43778	BRD-K08109516	PHH	10 uM	24 h	0.22	0.93	0.05	-0.28	-0.96	0.43
44059	BRD-K08109516	SKB	10 uM	24 h	-0.2	-0.85	0.01	-0.22	-0.73	0.04
100026	BRD-K08109516	U2OS	10 uM	6 h	0.0	0.0	0.0	0.26	0.91	0.23

Summary