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CMap Candidate Details

Structure:
CMap ID: C02957
Pert ID: BRD-K15791587
Compound Name: L-733060
Targets: TACR1
MoA: tachykinin antagonist
SMILES: FC(F)(F)c1cc(CO[C@H]2CCCN[C@H]2c2ccccc2)cc(c1)C(F)(F)F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1558 BRD-K15791587 HA1E 10 uM 24 h 0.29 1.23 0.5 0.0 0.0 0.0
1895 BRD-K15791587 HCC515 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.85
2379 BRD-K15791587 PC3 10 uM 6 h 0.0 0.0 0.0 -0.47 -1.58 15.65
2563 BRD-K15791587 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41736 BRD-K15791587 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41915 BRD-K15791587 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42312 BRD-K15791587 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42643 BRD-K15791587 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.31 1.08 0.66
42947 BRD-K15791587 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43301 BRD-K15791587 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43503 BRD-K15791587 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43803 BRD-K15791587 PHH 10 uM 24 h 0.23 0.96 0.07 -0.29 -0.99 0.51
44080 BRD-K15791587 SKB 10 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.59
100140 BRD-K15791587 U2OS 10 uM 6 h 0.21 0.89 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).