CMap Candidate Details
Structure:
| CMap ID: | C02983 |
| Pert ID: | BRD-K10961822 |
| Compound Name: | latanoprost |
| Targets: | PTGFR |
| MoA: | prostanoid receptor agonist |
| SMILES: | CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCc1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 25491 | BRD-K10961822 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.3 | 1.6 |
| 91078 | BRD-K10961822 | HUH7 | 8 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121166 | BRD-K10961822 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121202 | BRD-K10961822 | A549 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121237 | BRD-K10961822 | HA1E | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121294 | BRD-K10961822 | MCF??7.00 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121329 | BRD-K10961822 | PC3 | 0.04 uM | 24 h | -0.21 | -0.86 | 0.02 | -0.42 | -1.41 | 2.02 |
| 129282 | BRD-K10961822 | HELA | 2.22 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129316 | BRD-K10961822 | HT29 | 0.08 uM | 24 h | -0.22 | -0.91 | 0.05 | 0.0 | 0.0 | 0.0 |
| 129387 | BRD-K10961822 | YAPC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |