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CMap Candidate Details

Structure:
CMap ID: C03009
Pert ID: BRD-K03289534
Compound Name: lersivirine
Targets:
MoA: non-nucleoside reverse transcriptase inhibitor
SMILES: CCc1nn(CCO)c(CC)c1Oc1cc(cc(c1)C#N)C#N
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122922 BRD-K03289534 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122954 BRD-K03289534 HELA 0.125 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.71
123047 BRD-K03289534 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123084 BRD-K03289534 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123137 BRD-K03289534 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123207 BRD-K03289534 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131221 BRD-K03289534 A375 0.74 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.36
131263 BRD-K03289534 A549 2.22 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
131294 BRD-K03289534 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131331 BRD-K03289534 HT29 0.74 uM 24 h -0.27 -1.13 0.41 0.0 0.0 0.0
131384 BRD-K03289534 HUVEC 0.74 uM 24 h -0.29 -1.22 0.6 0.0 0.0 0.0
131419 BRD-K03289534 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131476 BRD-K03289534 PC3 0.08 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.07
131517 BRD-K03289534 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).