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CMap Candidate Details

Structure:
CMap ID: C03013
Pert ID: BRD-K94288301
Compound Name: letermovir
Targets:
MoA: CMV terminase inhibitor
SMILES: COc1cccc(c1)N1CCN(CC1)C1=Nc2c(F)cccc2[C@H](CC(O)=O)N1c1cc(ccc1OC)C(F)(F)F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128115 BRD-K94288301 A375 0.37 uM 24 h -0.24 -0.98 0.13 0.0 0.0 0.0
128145 BRD-K94288301 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128172 BRD-K94288301 HEK293 10 uM 24 h 0.21 0.9 0.02 -0.25 -0.83 0.16
128234 BRD-K94288301 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.58
128313 BRD-K94288301 MDAMB231 0.37 uM 24 h 0.17 0.73 0.0 0.0 0.0 0.0
128335 BRD-K94288301 PC3 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
128358 BRD-K94288301 THP1 10 uM 24 h -0.29 -1.22 0.62 -0.27 -0.92 0.32
135818 BRD-K94288301 HA1E 0.74 uM 24 h 0.24 1.0 0.1 0.0 0.0 0.0
135908 BRD-K94288301 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135949 BRD-K94288301 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135997 BRD-K94288301 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136033 BRD-K94288301 MCF??7.00 0.01 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
136143 BRD-K94288301 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).