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CMap Candidate Details

Structure:
CMap ID: C03022
Pert ID: BRD-K73107279
Compound Name: levamisole
Targets: ALPL|ALPPL2|CHRNA3
MoA: acetylcholine receptor agonist
SMILES: C1CN2C[C@@H](N=C2S1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91462 BRD-K73107279 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99439 BRD-K73107279 U2OS 10 uM 6 h 0.22 0.91 0.03 0.32 1.15 0.88
126640 BRD-K73107279 A375 1.11 uM 24 h -0.25 -1.02 0.18 0.0 0.0 0.0
126729 BRD-K73107279 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126753 BRD-K73107279 HT29 0.04 uM 24 h 0.3 1.24 0.52 0.0 0.0 0.0
126818 BRD-K73107279 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126860 BRD-K73107279 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
126904 BRD-K73107279 MDAMB231 10 uM 24 h 0.23 0.97 0.08 0.26 0.92 0.26
126923 BRD-K73107279 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126974 BRD-K73107279 THP1 0.125 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.91
134711 BRD-K73107279 A549 0.25 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.62
134746 BRD-K73107279 HA1E 0.01 uM 24 h -0.22 -0.91 0.05 0.23 0.81 0.09
134781 BRD-K73107279 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134888 BRD-K73107279 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.35 1.24 1.28
134910 BRD-K73107279 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135004 BRD-K73107279 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).