CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03030
Pert ID:	BRD-K33453211
Compound Name:	levocabastine
Targets:	HRH1\|NTSR2
MoA:	histamine receptor antagonist
SMILES:	C[C@@H]1CN(CC[C@]1(C(O)=O)c1ccccc1)[C@H]1CC[C@](CC1)(C#N)c1ccc(F)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4417	BRD-K33453211	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
4923	BRD-K33453211	VCAP	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.96	0.44
40793	BRD-K33453211	NEU	10 uM	24 h	0.3	1.24	0.53	0.3	1.07	0.64
41095	BRD-K33453211	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41428	BRD-K33453211	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99856	BRD-K33453211	U2OS	4 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
120559	BRD-K33453211	A549	0.04 uM	24 h	0.0	0.0	0.0	0.31	1.11	0.73
120598	BRD-K33453211	HA1E	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120622	BRD-K33453211	HELA	0.04 uM	24 h	0.0	0.0	0.0	0.32	1.12	0.77
120661	BRD-K33453211	HT29	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120713	BRD-K33453211	JURKAT	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120780	BRD-K33453211	PC3	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120822	BRD-K33453211	YAPC	0.04 uM	24 h	0.0	0.0	0.0	-0.26	-0.86	0.22
128987	BRD-K33453211	A375	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129055	BRD-K33453211	MCF??7.00	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary