CMap Candidate Details
Structure:
| CMap ID: | C03033 |
| Pert ID: | BRD-K27184429 |
| Compound Name: | levocetirizine |
| Targets: | HRH1 |
| MoA: | histamine receptor antagonist |
| SMILES: | OC(=O)COCCN1CCN(CC1)[C@H](c1ccccc1)c1ccc(Cl)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 25498 | BRD-K27184429 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120896 | BRD-K27184429 | A549 | 0.04 uM | 24 h | -0.2 | -0.85 | 0.01 | 0.25 | 0.88 | 0.18 |
| 120922 | BRD-K27184429 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120977 | BRD-K27184429 | HEK293 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121006 | BRD-K27184429 | HELA | 10 uM | 3 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.28 | 1.45 |
| 121060 | BRD-K27184429 | MCF??7.00 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121134 | BRD-K27184429 | YAPC | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129104 | BRD-K27184429 | A375 | 2.22 uM | 24 h | 0.22 | 0.92 | 0.04 | 0.26 | 0.92 | 0.24 |
| 129207 | BRD-K27184429 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129235 | BRD-K27184429 | PC3 | 0.01 uM | 24 h | 0.34 | 1.41 | 1.03 | 0.0 | 0.0 | 0.0 |