Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03036
Pert ID: BRD-K09471561
Compound Name: levofloxacin
Targets: TOP2A
MoA: bacterial DNA gyrase inhibitor
SMILES: C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24748 BRD-K09471561 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25489 BRD-K09471561 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91468 BRD-K09471561 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
100049 BRD-K09471561 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.68
121153 BRD-K09471561 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121190 BRD-K09471561 A549 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
121268 BRD-K09471561 HELA 0.125 uM 3 h 0.0 0.0 0.0 0.24 0.86 0.15
121289 BRD-K09471561 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121347 BRD-K09471561 YAPC 0.04 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
129301 BRD-K09471561 HT29 0.01 uM 24 h -0.31 -1.3 0.81 -0.36 -1.21 1.24
129353 BRD-K09471561 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).