CMap Candidate Details
Structure:
| CMap ID: | C03039 |
| Pert ID: | BRD-K35559145 |
| Compound Name: | levomepromazine |
| Targets: | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|DRD1|DRD2|DRD3|DRD4|DRD5|HRH1|HTR2A|HTR2C |
| MoA: | dopamine receptor antagonist |
| SMILES: | COc1ccc2Sc3ccccc3N(C[C@H](C)CN(C)C)c2c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 3010 | BRD-K35559145 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3184 | BRD-K35559145 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3614 | BRD-K35559145 | PC3 | 10 uM | 6 h | -0.3 | -1.25 | 0.68 | 0.0 | 0.0 | 0.0 |
| 3777 | BRD-K35559145 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.78 | 0.07 |
| 42092 | BRD-K35559145 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.94 | 0.28 |
| 42355 | BRD-K35559145 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 42681 | BRD-K35559145 | HEPG2 | 10 uM | 6 h | -0.26 | -1.07 | 0.27 | 0.0 | 0.0 | 0.0 |
| 42985 | BRD-K35559145 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.2 | -0.69 | 0.02 |
| 43187 | BRD-K35559145 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 43546 | BRD-K35559145 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.05 | 0.71 |
| 43844 | BRD-K35559145 | PHH | 10 uM | 24 h | -0.21 | -0.88 | 0.03 | 0.31 | 1.11 | 0.74 |
| 44111 | BRD-K35559145 | SKB | 10 uM | 24 h | -0.18 | -0.77 | 0.0 | -0.21 | -0.72 | 0.04 |