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CMap Candidate Details

Structure:
CMap ID: C00304
Pert ID: BRD-K23335153
Compound Name: AMN-082
Targets: GRM7
MoA: glutamate receptor modulator
SMILES: C(CNC(c1ccccc1)c1ccccc1)NC(c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4083 BRD-K23335153 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.4
4394 BRD-K23335153 HCC515 10 uM 24 h 0.2 0.85 0.01 -0.26 -0.88 0.25
4789 BRD-K23335153 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5057 BRD-K23335153 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39104 BRD-K23335153 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39309 BRD-K23335153 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39650 BRD-K23335153 ASC 10 uM 24 h 0.0 0.0 0.0 0.34 1.22 1.15
39966 BRD-K23335153 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.27 0.94 0.29
40243 BRD-K23335153 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40600 BRD-K23335153 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.35 1.25 1.29
40772 BRD-K23335153 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41073 BRD-K23335153 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41404 BRD-K23335153 SKB 10 uM 24 h -0.26 -1.1 0.35 -0.25 -0.84 0.18
99759 BRD-K23335153 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).