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CMap Candidate Details

Structure:
CMap ID: C03040
Pert ID: BRD-A67616246
Compound Name: levomequitazine
Targets: HRH1
MoA: histamine receptor antagonist
SMILES: C(C1CN2CCC1CC2)N1c2ccccc2Sc2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96336 BRD-A67616246 A375 10 uM 24 h -0.2 -0.84 0.01 0.32 1.14 0.87
96406 BRD-A67616246 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124602 BRD-A67616246 A549 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
124625 BRD-A67616246 HA1E 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
124643 BRD-A67616246 HEK293 10 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
124670 BRD-A67616246 HELA 10 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
124705 BRD-A67616246 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124767 BRD-A67616246 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124895 BRD-A67616246 THP1 0.125 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.16
124919 BRD-A67616246 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132844 BRD-A67616246 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.03
132882 BRD-A67616246 MCF10A 0.01 uM 24 h 0.3 1.24 0.53 0.26 0.92 0.26
132921 BRD-A67616246 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).