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CMap Candidate Details

Structure:
CMap ID: C03047
Pert ID: BRD-A30655177
Compound Name: LFM-A13
Targets: BTK
MoA: Bruton's tyrosine kinase (BTK) inhibitor
SMILES: CC(=O)C(C#N)C(=O)Nc1cc(Br)ccc1Br
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3676 BRD-A30655177 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8868 BRD-A30655177 A375 100 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
9282 BRD-A30655177 AGS 100 uM 6 h -0.24 -0.98 0.13 0.0 0.0 0.0
9586 BRD-A30655177 H1299 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9904 BRD-A30655177 HA1E 100 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10281 BRD-A30655177 HCC515 100 uM 6 h -0.26 -1.07 0.28 -0.29 -0.96 0.44
10394 BRD-A30655177 HCT116 100 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.26
10662 BRD-A30655177 HEPG2 100 uM 6 h -0.23 -0.94 0.08 0.22 0.77 0.06
10901 BRD-A30655177 HT29 100 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11161 BRD-A30655177 MCF??7.00 100 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11903 BRD-A30655177 NCIH596 100 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.2
12200 BRD-A30655177 NOMO1 100 uM 6 h -0.26 -1.09 0.33 0.0 0.0 0.0
12471 BRD-A30655177 PC3 100 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12660 BRD-A30655177 SW480 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12984 BRD-A30655177 THP1 100 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.41
13140 BRD-A30655177 U937 100 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39269 BRD-A30655177 A549 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
39561 BRD-A30655177 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40986 BRD-A30655177 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41310 BRD-A30655177 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87322 BRD-A30655177 BJAB 2.5 uM 6 h 0.23 0.95 0.06 0.0 0.0 0.0
87347 BRD-A30655177 HBL1 0.01 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.4
87397 BRD-A30655177 K562 2.5 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
87444 BRD-A30655177 KMS34 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87484 BRD-A30655177 MINO 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
87548 BRD-A30655177 NALM6 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.06
87599 BRD-A30655177 OCILY10 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87649 BRD-A30655177 OCILY19 2.5 uM 24 h -0.23 -0.95 0.09 0.31 1.1 0.71
87701 BRD-A30655177 OCILY3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87748 BRD-A30655177 SKMEL5 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87829 BRD-A30655177 TMD8 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
91365 BRD-A30655177 HUH7 1.11 uM 72 h 0.26 1.1 0.24 0.0 0.0 0.0
95695 BRD-A30655177 U2OS 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).