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CMap Candidate Details

Structure:
CMap ID: C03061
Pert ID: BRD-K05906022
Compound Name: limonin
Targets:
MoA: HIV protease inhibitor
SMILES: CC1(C)O[C@H]2CC(=O)OC[C@@]22[C@H]1CC(=O)[C@]1(C)[C@@H]2CC[C@@]2(C)[C@@H](OC(=O)[C@H]3O[C@@]123)c1ccoc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1535 BRD-K05906022 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
2072 BRD-K05906022 HCC515 10 uM 6 h 0.0 0.0 0.0 0.36 1.28 1.37
2210 BRD-K05906022 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2699 BRD-K05906022 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41710 BRD-K05906022 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41903 BRD-K05906022 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42271 BRD-K05906022 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42607 BRD-K05906022 HEPG2 10 uM 6 h -0.3 -1.25 0.71 -0.2 -0.67 0.02
42911 BRD-K05906022 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43284 BRD-K05906022 MCF??7.00 10 uM 6 h 0.25 1.04 0.16 0.0 0.0 0.0
43466 BRD-K05906022 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
43773 BRD-K05906022 PHH 10 uM 24 h 0.28 1.17 0.37 0.0 0.0 0.0
44052 BRD-K05906022 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100001 BRD-K05906022 U2OS 10 uM 6 h 0.0 0.0 0.0 0.29 1.02 0.49
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).