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CMap Candidate Details

Structure:
CMap ID: C03063
Pert ID: BRD-K96550715
Compound Name: linagliptin
Targets: DPP4
MoA: dipeptidyl peptidase inhibitor
SMILES: CC#CCn1c(nc2n(C)c(=O)n(Cc3nc(C)c4ccccc4n3)c(=O)c12)N1CCC[C@@H](N)C1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95330 BRD-K96550715 A549 10 uM 6 h 0.24 0.99 0.09 0.3 1.06 0.6
95357 BRD-K96550715 MCF??7.00 10 uM 48 h 0.25 1.02 0.13 0.0 0.0 0.0
95381 BRD-K96550715 U2OS 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96606 BRD-K96550715 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96678 BRD-K96550715 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120603 BRD-K96550715 HA1E 3.33 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
120626 BRD-K96550715 HELA 0.04 uM 24 h 0.24 0.98 0.09 0.28 1.0 0.43
120669 BRD-K96550715 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120721 BRD-K96550715 JURKAT 10 uM 24 h -0.23 -0.98 0.12 0.29 1.04 0.56
120830 BRD-K96550715 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).