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CMap Candidate Details

Structure:
CMap ID: C03080
Pert ID: BRD-K67966701
Compound Name: lisinopril
Targets: ACE|ACE2
MoA: angiotensin converting enzyme inhibitor
SMILES: NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91472 BRD-K67966701 HUH7 8 uM 72 h 0.0 0.0 0.0 -0.22 -0.73 0.05
126618 BRD-K67966701 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126758 BRD-K67966701 JURKAT 0.37 uM 24 h -0.28 -1.15 0.44 0.0 0.0 0.0
126791 BRD-K67966701 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126822 BRD-K67966701 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126925 BRD-K67966701 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134690 BRD-K67966701 A549 0.01 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
134715 BRD-K67966701 HA1E 0.74 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.26
134749 BRD-K67966701 HEK293 0.03 uM 24 h 0.21 0.86 0.01 -0.24 -0.8 0.12
134783 BRD-K67966701 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134812 BRD-K67966701 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134839 BRD-K67966701 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.12
134937 BRD-K67966701 MDAMB231 0.74 uM 24 h 0.24 1.01 0.12 0.0 0.0 0.0
134950 BRD-K67966701 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134979 BRD-K67966701 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).