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CMap Candidate Details

Structure:
CMap ID: C03081
Pert ID: BRD-A05334458
Compound Name: lisofylline
Targets:
MoA: interleukin receptor antagonist; STAT inhibitor
SMILES: CC(O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122537 BRD-A05334458 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122568 BRD-A05334458 A549 3.33 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.6
122624 BRD-A05334458 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122653 BRD-A05334458 HELA 0.37 uM 24 h -0.26 -1.07 0.28 -0.32 -1.06 0.74
122705 BRD-A05334458 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122786 BRD-A05334458 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130905 BRD-A05334458 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130992 BRD-A05334458 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131027 BRD-A05334458 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131076 BRD-A05334458 MCF??7.00 2.22 uM 24 h -0.2 -0.81 0.0 0.0 0.0 0.0
131110 BRD-A05334458 MDAMB231 2.22 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
131174 BRD-A05334458 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).