CMap Candidate Details
Structure:
| CMap ID: | C03092 |
| Pert ID: | BRD-K66206289 |
| Compound Name: | lobeline |
| Targets: | CHRNA10|CHRNA9|SLC18A2 |
| MoA: | acetylcholine receptor antagonist |
| SMILES: | CN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1CC(=O)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24468 | BRD-K66206289 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24692 | BRD-K66206289 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.89 | 0.21 |
| 24800 | BRD-K66206289 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24935 | BRD-K66206289 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25105 | BRD-K66206289 | MCF??7.00 | 10 uM | 6 h | 0.32 | 1.34 | 0.89 | 0.39 | 1.37 | 1.97 |
| 25179 | BRD-K66206289 | PC3 | 10 uM | 24 h | -0.3 | -1.24 | 0.64 | 0.34 | 1.21 | 1.15 |
| 25405 | BRD-K66206289 | VCAP | 10 uM | 24 h | 0.3 | 1.25 | 0.53 | -0.33 | -1.1 | 0.86 |
| 99348 | BRD-K66206289 | U2OS | 6.66 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |