Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03095
Pert ID: BRD-K66937583
Compound Name: lodoxamide
Targets:
MoA: histamine receptor antagonist
SMILES: OC(=O)C(=O)Nc1cc(cc(NC(=O)C(O)=O)c1Cl)C#N
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124641 BRD-K66937583 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
124665 BRD-K66937583 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124728 BRD-K66937583 JURKAT 1.11 uM 24 h 0.32 1.33 0.84 -0.28 -0.94 0.38
124745 BRD-K66937583 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124803 BRD-K66937583 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124844 BRD-K66937583 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124886 BRD-K66937583 THP1 0.125 uM 24 h 0.22 0.91 0.03 0.0 0.0 0.0
132666 BRD-K66937583 A375 0.03 uM 24 h -0.29 -1.22 0.61 0.3 1.05 0.58
132693 BRD-K66937583 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132724 BRD-K66937583 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132813 BRD-K66937583 HT29 0.74 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.26
132903 BRD-K66937583 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132957 BRD-K66937583 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).