CMap Candidate Details
Structure:
| CMap ID: | C03097 |
| Pert ID: | BRD-K82147103 |
| Compound Name: | lofepramine |
| Targets: | HTR1A|SLC6A2|SLC6A4 |
| MoA: | norepinephrine reuptake inhibitor; serotonin norepinephrine reuptake inhibitor (SNRI) |
| SMILES: | CN(CCCN1c2ccccc2CCc2ccccc12)CC(=O)c1ccc(Cl)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24485 | BRD-K82147103 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.87 | 0.17 |
| 24695 | BRD-K82147103 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.16 | 0.91 |
| 24950 | BRD-K82147103 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.04 | 0.65 |
| 25047 | BRD-K82147103 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.34 |
| 25193 | BRD-K82147103 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.98 | 0.48 |
| 25428 | BRD-K82147103 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |