CMap Candidate Details
Structure:
| CMap ID: | C03112 |
| Pert ID: | BRD-K55013654 |
| Compound Name: | lorcaserin |
| Targets: | HTR2A|HTR2B|HTR2C |
| MoA: | serotonin receptor agonist |
| SMILES: | C[C@H]1CNCCc2ccc(Cl)cc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 124358 | BRD-K55013654 | HELA | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124389 | BRD-K55013654 | HT29 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124426 | BRD-K55013654 | JURKAT | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.33 |
| 132337 | BRD-K55013654 | A375 | 0.08 uM | 24 h | -0.2 | -0.81 | 0.0 | 0.26 | 0.91 | 0.24 |
| 132364 | BRD-K55013654 | A549 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132393 | BRD-K55013654 | HA1E | 0.25 uM | 24 h | -0.3 | -1.27 | 0.74 | 0.0 | 0.0 | 0.0 |
| 132429 | BRD-K55013654 | HEK293 | 2.22 uM | 24 h | -0.21 | -0.86 | 0.02 | 0.0 | 0.0 | 0.0 |
| 132500 | BRD-K55013654 | MCF10A | 0.25 uM | 24 h | 0.26 | 1.1 | 0.25 | 0.0 | 0.0 | 0.0 |
| 132528 | BRD-K55013654 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132557 | BRD-K55013654 | MDAMB231 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132574 | BRD-K55013654 | PC3 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132614 | BRD-K55013654 | THP1 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132646 | BRD-K55013654 | YAPC | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.87 | 0.23 |