Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03115
Pert ID: BRD-A29854054
Compound Name: lorglumide
Targets: CCKAR|CCKBR
MoA: CCK receptor antagonist
SMILES: CCCCCN(CCCCC)C(=O)C(CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91478 BRD-A29854054 HUH7 6.66 uM 72 h -0.27 -1.12 0.38 0.0 0.0 0.0
121956 BRD-A29854054 HEK293 0.125 uM 24 h 0.22 0.91 0.04 0.24 0.86 0.15
122009 BRD-A29854054 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122047 BRD-A29854054 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122140 BRD-A29854054 MDAMB231 3.33 uM 24 h 0.26 1.08 0.22 0.0 0.0 0.0
122191 BRD-A29854054 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122219 BRD-A29854054 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130183 BRD-A29854054 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130202 BRD-A29854054 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130226 BRD-A29854054 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130288 BRD-A29854054 HELA 2.22 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.54
130348 BRD-A29854054 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130397 BRD-A29854054 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130432 BRD-A29854054 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
130478 BRD-A29854054 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).