CMap Candidate Details
Structure:
| CMap ID: | C00312 |
| Pert ID: | BRD-K24771047 |
| Compound Name: | ampalex |
| Targets: | GRIA1|GRIA2|GRIA3|GRIA4 |
| MoA: | glutamate receptor agonist |
| SMILES: | O=C(N1CCCCC1)c1ccc2nccnc2c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121948 | BRD-K24771047 | HEK293 | 0.125 uM | 24 h | -0.31 | -1.31 | 0.82 | 0.0 | 0.0 | 0.0 |
| 121998 | BRD-K24771047 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.74 | 0.06 |
| 122031 | BRD-K24771047 | HUVEC | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122131 | BRD-K24771047 | MDAMB231 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130178 | BRD-K24771047 | A375 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130193 | BRD-K24771047 | A549 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130215 | BRD-K24771047 | HA1E | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.24 | 1.3 |
| 130277 | BRD-K24771047 | HELA | 0.03 uM | 24 h | -0.23 | -0.98 | 0.12 | 0.0 | 0.0 | 0.0 |
| 130333 | BRD-K24771047 | JURKAT | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.96 | 0.43 |
| 130386 | BRD-K24771047 | MCF10A | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130425 | BRD-K24771047 | MCF??7.00 | 2.22 uM | 24 h | 0.3 | 1.26 | 0.56 | -0.25 | -0.83 | 0.15 |
| 130472 | BRD-K24771047 | PC3 | 0.25 uM | 24 h | -0.19 | -0.8 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130488 | BRD-K24771047 | THP1 | 2.22 uM | 24 h | -0.26 | -1.09 | 0.32 | 0.26 | 0.91 | 0.23 |
| 130513 | BRD-K24771047 | YAPC | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |