CMap Candidate Details
Structure:
| CMap ID: | C03133 |
| Pert ID: | BRD-K31309378 |
| Compound Name: | lucitanib |
| Targets: | FGFR1|FLT1|KDR|KIT|PDGFRA|PDGFRB|RET |
| MoA: | FGFR inhibitor; VEGFR inhibitor |
| SMILES: | CNC(=O)c1cccc2cc(ccc12)Oc1ccnc2cc(OCC3(N)CC3)c(OC)cc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 90858 | BRD-K31309378 | MCF10A | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120510 | BRD-K31309378 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120543 | BRD-K31309378 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120615 | BRD-K31309378 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.79 | 0.07 |
| 120644 | BRD-K31309378 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.01 | 0.58 |
| 120694 | BRD-K31309378 | JURKAT | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120747 | BRD-K31309378 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120768 | BRD-K31309378 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120800 | BRD-K31309378 | YAPC | 10 uM | 24 h | -0.27 | -1.14 | 0.42 | 0.22 | 0.79 | 0.07 |
| 129000 | BRD-K31309378 | HA1E | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.18 | -0.62 | 0.0 |