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CMap Candidate Details

Structure:
CMap ID: C03136
Pert ID: BRD-K71058253
Compound Name: luliconazole
Targets:
MoA: sterol demethylase inhibitor
SMILES: Clc1ccc([C@@H]2CS\C(S2)=C(\C#N)n2ccnc2)c(Cl)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126633 BRD-K71058253 A375 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.68
126785 BRD-K71058253 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126808 BRD-K71058253 MCF10A 10 uM 24 h -0.18 -0.75 0.0 0.0 0.0 0.0
126849 BRD-K71058253 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126893 BRD-K71058253 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.21
126919 BRD-K71058253 PC3 10 uM 24 h -0.24 -0.98 0.12 0.33 1.18 0.99
126961 BRD-K71058253 THP1 10 uM 24 h -0.32 -1.34 0.98 0.0 0.0 0.0
134707 BRD-K71058253 A549 2.22 uM 24 h 0.0 0.0 0.0 0.39 1.4 2.18
134735 BRD-K71058253 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134770 BRD-K71058253 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134799 BRD-K71058253 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.26 0.94 0.28
134831 BRD-K71058253 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134875 BRD-K71058253 HUVEC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134996 BRD-K71058253 YAPC 0.74 uM 24 h -0.22 -0.9 0.05 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).