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CMap Candidate Details

Structure:
CMap ID: C03145
Pert ID: BRD-K67013324
Compound Name: luzindole
Targets: MTNR1A|MTNR1B
MoA: melatonin receptor antagonist
SMILES: CC(=O)NCCc1c(Cc2ccccc2)[nH]c2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1606 BRD-K67013324 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2114 BRD-K67013324 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2193 BRD-K67013324 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2492 BRD-K67013324 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41826 BRD-K67013324 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42129 BRD-K67013324 A549 10 uM 6 h -0.18 -0.77 0.0 -0.34 -1.14 1.02
42440 BRD-K67013324 ASC 10 uM 24 h -0.25 -1.04 0.21 0.0 0.0 0.0
42755 BRD-K67013324 HEPG2 10 uM 6 h -0.19 -0.77 0.0 -0.34 -1.13 1.0
43054 BRD-K67013324 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43224 BRD-K67013324 MCF??7.00 10 uM 24 h -0.2 -0.83 0.0 -0.28 -0.96 0.42
43921 BRD-K67013324 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44176 BRD-K67013324 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98417 BRD-K67013324 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98708 BRD-K67013324 NPC 10 uM 6 h 0.0 0.0 0.0 0.35 1.22 1.18
99358 BRD-K67013324 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).