CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03154
Pert ID:	BRD-K93331255
Compound Name:	lypressin
Targets:	AVPR1A\|AVPR1B\|AVPR2
MoA:	vasopressin receptor agonist
SMILES:	NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
33703	BRD-K93331255	A375	10 uM	6 h	0.0	0.0	0.0	-0.27	-0.93	0.34
33858	BRD-K93331255	A549	10 uM	24 h	0.26	1.08	0.22	-0.31	-1.06	0.73
34212	BRD-K93331255	ASC	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.06	0.73
34447	BRD-K93331255	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
34993	BRD-K93331255	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35229	BRD-K93331255	HT29	10 uM	6 h	0.0	0.0	0.0	0.24	0.85	0.14
35476	BRD-K93331255	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	-0.29	-0.99	0.51
35639	BRD-K93331255	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
35867	BRD-K93331255	NPC	10 uM	24 h	0.0	0.0	0.0	-0.26	-0.86	0.22
36013	BRD-K93331255	PC3	10 uM	24 h	0.0	0.0	0.0	0.28	0.98	0.37
36384	BRD-K93331255	PHH	10 uM	24 h	0.0	0.0	0.0	-0.2	-0.67	0.01
36685	BRD-K93331255	SKB	10 uM	24 h	0.0	0.0	0.0	-0.39	-1.32	1.71
36896	BRD-K93331255	VCAP	10 uM	24 h	0.0	0.0	0.0	-0.24	-0.79	0.11

Summary