CMap Candidate Details
Structure:
CMap ID: | C03155 |
Pert ID: | BRD-K78055238 |
Compound Name: | LY2090314 |
Targets: | GSK3B |
MoA: | glycogen synthase kinase inhibitor |
SMILES: | Fc1cc2CN(CCn3cc(C4=C(C(=O)NC4=O)c4cnc5ccccn45)c(c1)c23)C(=O)N1CCCCC1 |
InchiKey: | |
Compound Aliases: |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
127030 | BRD-K78055238 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
127113 | BRD-K78055238 | HELA | 1.11 uM | 24 h | 0.32 | 1.33 | 0.84 | 0.0 | 0.0 | 0.0 |
127149 | BRD-K78055238 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
127219 | BRD-K78055238 | MCF??7.00 | 3.33 uM | 24 h | 0.24 | 1.0 | 0.11 | 0.0 | 0.0 | 0.0 |
127252 | BRD-K78055238 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
127290 | BRD-K78055238 | THP1 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
127324 | BRD-K78055238 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
135056 | BRD-K78055238 | A549 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
135091 | BRD-K78055238 | HA1E | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.17 | 1.12 |
135113 | BRD-K78055238 | HEK293 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
135183 | BRD-K78055238 | JURKAT | 0.08 uM | 24 h | 0.27 | 1.13 | 0.3 | 0.31 | 1.09 | 0.67 |
135216 | BRD-K78055238 | MCF10A | 0.74 uM | 24 h | 0.25 | 1.03 | 0.13 | 0.4 | 1.42 | 2.19 |
135281 | BRD-K78055238 | MDAMB231 | 0.25 uM | 24 h | 0.25 | 1.03 | 0.13 | 0.0 | 0.0 | 0.0 |