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CMap Candidate Details

Structure:
CMap ID: C03159
Pert ID: BRD-K78118466
Compound Name: LY2157299
Targets: TGFBR1
MoA: TGF beta receptor inhibitor
SMILES: Cc1cccc(n1)-c1nn2CCCc2c1-c1ccnc2ccc(cc12)C(N)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127369 BRD-K78118466 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127404 BRD-K78118466 A549 10 uM 24 h -0.17 -0.71 0.0 0.0 0.0 0.0
127446 BRD-K78118466 HA1E 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
127490 BRD-K78118466 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127536 BRD-K78118466 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127624 BRD-K78118466 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127661 BRD-K78118466 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127709 BRD-K78118466 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135381 BRD-K78118466 HELA 2.22 uM 24 h -0.26 -1.08 0.29 0.0 0.0 0.0
135450 BRD-K78118466 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 -0.38 -1.26 1.39
135481 BRD-K78118466 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.84
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).