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CMap Candidate Details

Structure:
CMap ID: C03165
Pert ID: BRD-K04993719
Compound Name: LY2334737
Targets:
MoA: antitumor agent; ribonucleotide reductase inhibitor
SMILES: CCCC(CCC)C(=O)Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)c(=O)n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122536 BRD-K04993719 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122567 BRD-K04993719 A549 1.11 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.24
122672 BRD-K04993719 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122702 BRD-K04993719 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122745 BRD-K04993719 MCF??7.00 10 uM 24 h -0.28 -1.19 0.52 0.0 0.0 0.0
122763 BRD-K04993719 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.15
130902 BRD-K04993719 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130927 BRD-K04993719 HEK293 0.74 uM 24 h 0.26 1.09 0.22 0.0 0.0 0.0
130953 BRD-K04993719 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131024 BRD-K04993719 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131141 BRD-K04993719 PC3 0.03 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.39
131173 BRD-K04993719 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).