CMap Candidate Details
Structure:
| CMap ID: | C03175 |
| Pert ID: | BRD-K18961567 |
| Compound Name: | LY2801653 |
| Targets: | MET |
| MoA: | MET inhibitor |
| SMILES: | Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121359 | BRD-K18961567 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121398 | BRD-K18961567 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121432 | BRD-K18961567 | HT29 | 10 uM | 24 h | 0.25 | 1.04 | 0.14 | 0.32 | 1.13 | 0.84 |
| 121473 | BRD-K18961567 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121496 | BRD-K18961567 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129425 | BRD-K18961567 | HA1E | 2.22 uM | 24 h | 0.25 | 1.04 | 0.14 | 0.27 | 0.94 | 0.29 |
| 129510 | BRD-K18961567 | MCF??7.00 | 2.22 uM | 24 h | 0.25 | 1.05 | 0.17 | -0.27 | -0.91 | 0.31 |