CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03190
Pert ID:	BRD-K06234293
Compound Name:	LY364947
Targets:	TGFBR1
MoA:	TGF beta receptor inhibitor; p38 MAPK inhibitor
SMILES:	c1[nH]nc(c1-c1ccnc2ccccc12)-c1ccccn1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4046	BRD-K06234293	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
4348	BRD-K06234293	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5025	BRD-K06234293	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44662	BRD-K06234293	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44832	BRD-K06234293	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45143	BRD-K06234293	HEPG2	10 uM	6 h	0.0	0.0	0.0	-0.38	-1.27	1.44
45411	BRD-K06234293	HT29	10 uM	6 h	0.0	0.0	0.0	0.27	0.95	0.31
45642	BRD-K06234293	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45947	BRD-K06234293	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46266	BRD-K06234293	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46582	BRD-K06234293	SKB	10 uM	24 h	0.26	1.1	0.24	0.0	0.0	0.0
96474	BRD-K06234293	A375	10 uM	24 h	0.0	0.0	0.0	0.31	1.11	0.71
96540	BRD-K06234293	PC3	3.33 uM	24 h	0.32	1.32	0.79	0.2	0.72	0.02
97322	BRD-K06234293	HAP1	3.33 uM	24 h	0.0	0.0	0.0	0.33	1.17	0.93
100009	BRD-K06234293	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary