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CMap Candidate Details

Structure:
CMap ID: C03194
Pert ID: BRD-K87696786
Compound Name: LY456236
Targets: GRM1
MoA: glutamate receptor antagonist
SMILES: COc1ccc(Nc2ncnc3ccc(OC)cc23)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1651 BRD-K87696786 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2000 BRD-K87696786 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2440 BRD-K87696786 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2520 BRD-K87696786 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39211 BRD-K87696786 A375 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
39512 BRD-K87696786 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39805 BRD-K87696786 ASC 10 uM 24 h 0.22 0.92 0.04 -0.3 -1.02 0.61
40097 BRD-K87696786 HEPG2 10 uM 6 h -0.28 -1.15 0.44 0.0 0.0 0.0
40362 BRD-K87696786 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40524 BRD-K87696786 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41565 BRD-K87696786 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98437 BRD-K87696786 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98777 BRD-K87696786 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).