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CMap Candidate Details

Structure:
CMap ID: C03195
Pert ID: BRD-K36965586
Compound Name: m-Chlorophenylbiguanide
Targets: HTR3A|HTR3B
MoA:
SMILES: NC(=N)NC(=N)Nc1cccc(Cl)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2875 BRD-K36965586 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3187 BRD-K36965586 HCC515 10 uM 24 h 0.22 0.93 0.05 0.27 0.94 0.29
3618 BRD-K36965586 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3781 BRD-K36965586 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
44381 BRD-K36965586 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44698 BRD-K36965586 A549 10 uM 6 h -0.22 -0.92 0.06 0.0 0.0 0.0
44943 BRD-K36965586 ASC 10 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
45241 BRD-K36965586 HEPG2 10 uM 6 h -0.24 -0.98 0.13 -0.24 -0.8 0.11
45511 BRD-K36965586 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45690 BRD-K36965586 MCF??7.00 10 uM 24 h 0.23 0.96 0.08 0.0 0.0 0.0
46062 BRD-K36965586 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46378 BRD-K36965586 PHH 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.03
99894 BRD-K36965586 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).