CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03206
Pert ID:	BRD-K30649484
Compound Name:	mafenide
Targets:	CA12\|CA14\|CA2\|CA4\|CA6\|CA9
MoA:	carbonic anhydrase inhibitor
SMILES:	NCc1ccc(cc1)S(N)(=O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
19007	BRD-K30649484	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
19440	BRD-K30649484	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
19655	BRD-K30649484	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
19980	BRD-K30649484	HCC515	10 uM	6 h	0.0	0.0	0.0	-0.22	-0.74	0.05
20312	BRD-K30649484	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
20635	BRD-K30649484	HT29	10 uM	6 h	0.2	0.82	0.0	0.0	0.0	0.0
20886	BRD-K30649484	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
21451	BRD-K30649484	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
21732	BRD-K30649484	VCAP	10 uM	6 h	0.23	0.95	0.07	-0.37	-1.23	1.28

Summary