CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03229
Pert ID:	BRD-K32218650
Compound Name:	MBX-2982
Targets:	GPR119
MoA:	glucose dependent insulinotropic receptor agonist
SMILES:	CCc1cnc(nc1)N1CCC(CC1)c1nc(COc2ccc(cc2)-n2cnnn2)cs1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
121904	BRD-K32218650	A375	10 uM	24 h	0.0	0.0	0.0	-0.37	-1.26	1.35
121923	BRD-K32218650	A549	10 uM	24 h	0.23	0.96	0.07	-0.26	-0.89	0.27
121940	BRD-K32218650	HA1E	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121968	BRD-K32218650	HEK293	10 uM	24 h	-0.26	-1.1	0.35	0.0	0.0	0.0
122019	BRD-K32218650	HT29	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122067	BRD-K32218650	HUVEC	10 uM	24 h	-0.25	-1.05	0.23	0.0	0.0	0.0
122117	BRD-K32218650	MCF??7.00	10 uM	24 h	-0.2	-0.85	0.01	-0.4	-1.36	2.02
122150	BRD-K32218650	MDAMB231	3.33 uM	24 h	0.0	0.0	0.0	-0.29	-0.97	0.46
122172	BRD-K32218650	PC3	10 uM	24 h	0.21	0.9	0.02	0.0	0.0	0.0
122203	BRD-K32218650	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130301	BRD-K32218650	HELA	0.01 uM	24 h	0.0	0.0	0.0	-0.32	-1.07	0.75
130368	BRD-K32218650	JURKAT	0.25 uM	24 h	0.0	0.0	0.0	0.22	0.79	0.07
130412	BRD-K32218650	MCF10A	0.74 uM	24 h	0.0	0.0	0.0	-0.27	-0.91	0.3
130535	BRD-K32218650	YAPC	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary