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CMap Candidate Details

Structure:
CMap ID: C03234
Pert ID: BRD-K75844781
Compound Name: mCPP
Targets: HTR1A|HTR1D|HTR1E|HTR2A|HTR2B|HTR2C|HTR6
MoA: serotonin receptor agonist
SMILES: Clc1cccc(c1)N1CCNCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
99469 BRD-K75844781 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
127042 BRD-K75844781 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127098 BRD-K75844781 HELA 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127137 BRD-K75844781 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127164 BRD-K75844781 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127181 BRD-K75844781 MCF10A 0.37 uM 24 h 0.22 0.9 0.03 0.0 0.0 0.0
127281 BRD-K75844781 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127312 BRD-K75844781 YAPC 0.125 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.65
135016 BRD-K75844781 A375 0.01 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
135041 BRD-K75844781 A549 2.22 uM 24 h 0.32 1.35 0.94 0.27 0.96 0.34
135107 BRD-K75844781 HEK293 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135229 BRD-K75844781 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
135262 BRD-K75844781 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
135299 BRD-K75844781 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).