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CMap Candidate Details

Structure:
CMap ID: C03236
Pert ID: BRD-K92758126
Compound Name: MD-920
Targets: AADACL2
MoA: NFkB pathway inhibitor
SMILES: C[C@@]12[C@H]3[C@H](C(O)=O)[C@@]45CC(=C)[C@@](O)(C4)CC[C@H]5[C@]3(OC1=O)C=C[C@@H]2O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2143 BRD-K92758126 HCC515 10 uM 6 h 0.24 1.01 0.12 0.37 1.3 1.58
2457 BRD-K92758126 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41856 BRD-K92758126 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42158 BRD-K92758126 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42496 BRD-K92758126 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42806 BRD-K92758126 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.1
43671 BRD-K92758126 NPC 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
43972 BRD-K92758126 PHH 10 uM 24 h 0.0 0.0 0.0 0.2 0.72 0.03
128418 BRD-K92758126 HEK293 6.66 uM 24 h -0.28 -1.19 0.51 -0.39 -1.31 1.71
128492 BRD-K92758126 HT29 0.025 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
128528 BRD-K92758126 JURKAT 1.67 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128584 BRD-K92758126 MCF10A 6.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128621 BRD-K92758126 MDAMB231 0.07 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128671 BRD-K92758126 PC3 6.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128701 BRD-K92758126 THP1 6.66 uM 24 h 0.31 1.29 0.67 -0.29 -0.98 0.47
136208 BRD-K92758126 HA1E 1.25 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
136250 BRD-K92758126 HELA 0.5 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.39
136329 BRD-K92758126 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.31 1.08 0.66
136379 BRD-K92758126 YAPC 0.05 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).