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CMap Candidate Details

Structure:
CMap ID: C03240
Pert ID: BRD-K59753853
Compound Name: MDL-29951
Targets: FBP1
MoA: glutamate receptor antagonist
SMILES: OC(=O)CCc1c([nH]c2cc(Cl)cc(Cl)c12)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5219 BRD-K59753853 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5345 BRD-K59753853 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5792 BRD-K59753853 HCC515 10 uM 6 h 0.3 1.24 0.51 0.0 0.0 0.0
6290 BRD-K59753853 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6575 BRD-K59753853 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37405 BRD-K59753853 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37705 BRD-K59753853 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37928 BRD-K59753853 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.22 0.78 0.07
38100 BRD-K59753853 HT29 10 uM 6 h -0.2 -0.82 0.0 -0.36 -1.22 1.24
38238 BRD-K59753853 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38526 BRD-K59753853 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38755 BRD-K59753853 PHH 10 uM 24 h 0.0 0.0 0.0 -0.18 -0.62 0.0
38981 BRD-K59753853 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99708 BRD-K59753853 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).