CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03246
Pert ID:	BRD-A09467419
Compound Name:	mebeverine
Targets:	CHRM1
MoA:	acetylcholine receptor antagonist
SMILES:	CCN(CCCCOC(=O)c1ccc(OC)c(OC)c1)C(C)Cc1ccc(OC)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5144	BRD-A09467419	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5251	BRD-A09467419	HA1E	10 uM	24 h	0.0	0.0	0.0	0.27	0.97	0.35
5493	BRD-A09467419	HCC515	10 uM	24 h	0.0	0.0	0.0	0.34	1.2	1.13
5822	BRD-A09467419	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6233	BRD-A09467419	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6344	BRD-A09467419	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39260	BRD-A09467419	A549	10 uM	24 h	0.21	0.88	0.02	0.2	0.72	0.02
39546	BRD-A09467419	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
40162	BRD-A09467419	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40557	BRD-A09467419	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40679	BRD-A09467419	NEU	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.06	0.73
40972	BRD-A09467419	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41296	BRD-A09467419	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary